产品货号：
Z16759
中文名称：
FASL/FASLG抗体
英文名称：
Anti-FASL/FASLG Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FASL/FASLG Antibody |
| 指标别名 | Apoptosis antigen ligand;APT1LG1;APTL;CD178;CD95L;CD95 ligand;CD95L;Fas antigen ligand;Fas ligand;FASL;FASLG;TNFSF6 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | FASLG |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Fas Ligand(263-281aa ELSLVNFEESQTFFGLYKL). |
| 实际分子量 | 31KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Fas ligand(FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor(TNF) family.Its binding with its receptor induces apoptosis.The human FASL gene consists of approximately 8kb and is split into 4 exons.Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer.Fas ligand or FasL is a homotrimeric type II transmembrane protein.It signals through trimerization of FasR,which spans the membrane of the "target" cell.This trimerization usually leads to apoptosis,or cell death.Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external matrix metalloproteinase MMP-7. |
| Uniprot ID | P48023 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | Fas ligand(TNF superfamily,member 6) |
| 蛋白名全称 | Tumor necrosis factor ligand superfamily member 6 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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